Sitemap - 2023 - The Drug Development Letter

CAR T cells linked to secondary AML/MDS

Ash Update with Aaron Goodman

Observational studies and randomized trials

HLA-based therapeutics: an entire drug pipeline is based on a patient’s race.

How to read and interpret Kaplan Meier Curves

Giving adjuvant Xeloda to Biliary cancer was and is crazy

Anticoagulating people forever after unprovoked VTE lacks robust evidence

How much money do we waste when cancer patients change dose and throw out their pills?

ADAURA trial: An Unethical Trial

Treatment After Progression in Oncology Studies is Vitally Important

How to read and interpret a cancer clinical trial

Abbvie voluntarily recalls Ibrutinib in MCL and MZL

Can altering the microbiome improve how checkpoint inhibitors work?

Tumor Agnostic Drugs are Not Tumor Agnostic: An Analysis of Response Rate by Tumor Type

Real World Evidence - Danish Keynote Slides

Zuma 7 - crossover rate confirmed

Zuma 7 has OS benefit... Not so fast.

The starting dose is fair, but that is about it

Relapsed cancer patients die so asymptomatic pre-cancer patients can go on trial

NEW JAMA PAPER - MRD+ in AML prior to transplant does poorly. Stronger conditioning helps the young - Wait, Not So Fast

Ida-cel or Standard Regimens

Which Drugs is Medicare Expected to Negotiate?

More on Randomized Trials - Equivalence/ NI/ S, P values, control arms, crossover

Dostarlimab in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer: The Next Magic Bullet?

CodeBreaK 200 & Sotorasib

Randomized trials - the basics

How to search for, negotiate, and choose your first job

PSMA pet scans: Just because it is more sensitive doesn't make it better

Rucaparib vs. Investigator choice - Problems with TRITON-3

Coming soon