Each new , more-sensitive, test will "up-stage" a proportion of patients. This"stage migration" was referred to as the "Will Rogers phenomenon" in a classic NEJM paper four decades or so ago. An interesting spin off is that, if treatment protocols, stage for stage, remain constant, the "stage migration" results in an improved outcome at every stage, while of course the overall outcome for the population is unaffected
Each new , more-sensitive, test will "up-stage" a proportion of patients. This"stage migration" was referred to as the "Will Rogers phenomenon" in a classic NEJM paper four decades or so ago. An interesting spin off is that, if treatment protocols, stage for stage, remain constant, the "stage migration" results in an improved outcome at every stage, while of course the overall outcome for the population is unaffected