An Educational Opportunity... ESMO2024 and the LEAP-012 trial!
How a colleague's well-intended comments prompted me to explain several common misunderstandings that should be better taught during oncology training.
How it started: I made a comment after the LEAP-012 trial was presented at ESMO 2024. Here is the tweet.
Follows a 15+ tweets educational thread!
Unfortunately, not just oncology. Medicine and most of its drugs is delusional.
Great comments. If the sample size was enlarged to 3 times of the current sample size, then the P value would be below 0.025 with a HR=0.80, therefore, the LEAP-012 study met its OS endpoint.
With these results, do you think its rationale to provide pts with len and pembro?